Al donar muestras de sangre en su próxima extracción de laboratorio y permitir el acceso a sus registros médicos al biobanco, los investigadores pueden aprender más sobre lo que ayudará a combatir mejor las enfermedades que lo afectan a usted, a sus seres queridos, a las generaciones futuras y a la comunidad en general.
La participación es fácil y no se necesitan citas adicionales.
- Lea y firme el formulario de consentimiento del biobanco en su portal para pacientes My Health Connection.
- La próxima vez que su médico ordene una extracción de sangre, se recolectará una muestra de sangre adicional convenientemente para el biobanco sin costo alguno para usted.
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Devolución de resultados
The biobank is returning clinical genetic test results from a CLIA-certified and CAP-accredited laboratory that may be used by your provider or health care team to impact screening, diagnosis or treatment decisions.
Hay tres tipos de resultados de pruebas genéticas clínicas que el biobanco puede devolver:
- Riesgo de enfermedad: Resultados que pueden predecir el riesgo de padecer enfermedades, incluidos algunos tipos de cáncer, enfermedades cardíacas, enfermedades musculares y otras enfermedades.
- Farmacogenética: Resultados que pueden predecir su respuesta a ciertos medicamentos.
- Otro: Resultados que pueden predecir el riesgo de desarrollar ciertas enfermedades o afecciones.
Investigación
You could make an impact in the world of genetic research.
Privacy
We take the protection of your privacy very seriously. We follow federal privacy laws and health care regulations to protect your information.
Patient Story Highlight
Kristina Paul story intro will go here. I am just using this video as a placeholder for now.
It’s easy to participate
1. Enroll
If eligible, you can read and sign the consent form through your UCHealth My Health Connection account in the menu under “Research Opportunities”.
2. Provide a Sample
A biobank blood sample will be collected at a future UCHealth clinic blood draw (additionally, a saliva sample could be collected) which will be stored and processed in the secured and locked biobank laboratory.
3. DNA and Data
Your DNA will be extracted from the sample and analyzed, then your genetic data and medical record data will be linked, de-identified and added to data from 200,000+ other biobank participants.
4. Disease Research
We make biobank data available for approved studies so researchers can get a more comprehensive view of how genes influence health and disease.
5. Possible Genetic Test Results
If we learn something about you that may affect your health, we may be able to return this information to you through your My Health Connection account, or by phone or email.
Resultados de la farmacogenómica
Statins
ABCG2
ABCG2
The ABCG2 gene gives instructions to your body to make a protein. The ABCG2 protein helps carry the medicine, rosuvastatin, so your body can use it. Rosuvastatin is used to help lower cholesterol. The results of your ABCG2 gene test will place you into one of 3 groups: Normal function – People in this group are likely to have normal working ABCG2 proteins. Decreased function – People in this group may have reduced function of ABCG2 proteins. Poor function – People in this group may have very little or no active ABCG2 protein. Your ABCG2 gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.SLCO1B1
SLCO1B1
The SLCO1B1 gene provides instructions to your body to make a protein. This protein has a role in the body’s handling of certain medicines. These medicines include statins, which help lower cholesterol. These are the medicines that we know of right now that are broken down by SLCO1B1 proteins and affected by SLCO1B1 gene test results. Experts keep on finding new data about which medicines are affected by gene test results. The results of your SLCO1B1 gene test will place you into one of 3 groups: Normal function – Your genetic test results indicate that you likely have normal working SLCO1B1 proteins. Decreased function – Your genetic test results indicate that you likely have reduced function of SLCO1B1 proteins. Poor function – Your genetic test results indicate that you likely have very little or no working SLCO1B1 protein. Learn more about SLCO1B1. Your SLCO1B1 gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.
Blood Thinners
CYP4F2
CYP4F2
The CYP4F2 (say “SIP-4-ef-2”) gene tells your body how to make a protein. It is the job of the CYP4F2 protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your CYP4F2 gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working CYP4F2 proteins. Intermediate function: People in this group may have reduced activity of CYP4F2 proteins. Poor function: People in this group may have very little or no active CYP4F2 protein. Learn more about CYP4F2. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.Clúster CYP2C
Clúster CYP2C
The CYP2C (say “SIP-2-see”) cluster gene tells your body how to make a protein. It is the job of the CYP2C cluster protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your CYP2C cluster gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working CYP2C cluster proteins. Decreased function: People in this group may have reduced activity of CYP2C cluster proteins. Poor function: People in this group may have very little or no active CYP2C cluster protein. Learn more about CYP2C Cluster. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctorVKORC1
VKORC1
The VKORC1 (say “V-core-C-1”) gene tells your body how to make a protein. It is the job of the VKORC1 protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your VKORC1 gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working VKORC1 proteins. Decreased function: People in this group may have reduced activity of VKORC1 proteins. Poor function: People in this group may have very little or no active VKORC1 protein. Learn more about VKORC1. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.Antidepressants
CYP2C19
CYP2C19
The CYP2C19 (say “SIP-2-see-19”) gene provides instructions to your body to make a protein. It is the job of the CYP2C19 protein to break down a variety of certain medicines. Only certain medicines are impacted by this gene. The results of your CYP2C19 gene test will place you into one of 5 groups: Normal metabolizer – Your genetic test results indicate that you likely have normal working CYP2C19 proteins. Poor metabolizer – Your genetic test results indicate that you likely have very little or no active CYP2C19 proteins. Intermediate metabolizer – Your genetic test results indicate that you likely have reduced activity of CYP2C19 proteins. Rapid metabolizer – Your genetic test results indicate that you likely have high activity of CYP2C19 proteins. Ultrarapid metabolizer – Your genetic test results indicate that you likely have very high activity of CYP2C19 proteins. Learn more about CYP2C19. Your CYP2C19 gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.CYP2D6
CYP2D6
The CYP2D6 (say “SIP-2-de-6”) gene gives instructions to your body about how to make a protein. It is the job of the CYP2D6 protein to break down certain medicines. These medicines include: Some medicines that help with your mood or attention. Some medicines that are used to treat pain. Some medicines that are used to help with your muscles or fatigue. Eliglustat: Used to treat Gaucher Disease. Metoclopramide: Used to treat slow digestion because of diabetes mellitus or gastroesophageal reflux disease (GERD). Metoprolol: Used to treat some heart conditions or high blood pressure. Ondansetron: Used to treat nausea or vomiting. The results of your CYP2D6 gene test put you into 1 of 4 groups: Ultrarapid metabolizer: People in this group may have increased activity of CYP2D6 proteins. Normal metabolizer: People in this group are likely to have normal working CYP2D6 proteins. Intermediate metabolizer: People in this group may have reduced activity of CYP2D6 proteins. Poor metabolizer: People in this group may have very little or no active CYP2D6 protein. Learn more about CYP2D6. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.Clúster CYP2C
Clúster CYP2C
The CYP2C (say “SIP-2-see”) cluster gene tells your body how to make a protein. It is the job of the CYP2C cluster protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your CYP2C cluster gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working CYP2C cluster proteins. Decreased function: People in this group may have reduced activity of CYP2C cluster proteins. Poor function: People in this group may have very little or no active CYP2C cluster protein. Learn more about CYP2C Cluster. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor Protein Pump Inhibitors
CYP2C19
CYP2C19
The CYP2C19 (say “SIP-2-see-19”) gene provides instructions to your body to make a protein. It is the job of the CYP2C19 protein to break down a variety of certain medicines. Only certain medicines are impacted by this gene. The results of your CYP2C19 gene test will place you into one of 5 groups: Normal metabolizer – Your genetic test results indicate that you likely have normal working CYP2C19 proteins. Poor metabolizer – Your genetic test results indicate that you likely have very little or no active CYP2C19 proteins. Intermediate metabolizer – Your genetic test results indicate that you likely have reduced activity of CYP2C19 proteins. Rapid metabolizer – Your genetic test results indicate that you likely have high activity of CYP2C19 proteins. Ultrarapid metabolizer – Your genetic test results indicate that you likely have very high activity of CYP2C19 proteins. Learn more about CYP2C19. Your CYP2C19 gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.Clúster CYP2C
Clúster CYP2C
The CYP2C (say “SIP-2-see”) cluster gene tells your body how to make a protein. It is the job of the CYP2C cluster protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your CYP2C cluster gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working CYP2C cluster proteins. Decreased function: People in this group may have reduced activity of CYP2C cluster proteins. Poor function: People in this group may have very little or no active CYP2C cluster protein. Learn more about CYP2C Cluster. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor Immunosupressants
CYP3A5
CYP3A5
The CYP3A5 (say “SIP-3-ay-5”) gene tells your body how to make a protein. It is the job of the CYP3A5 protein to break down certain medicines. An example of this medicine is tacrolimus. This medicine is used after transplants and to treat certain skin diseases. The results of your CYP3A5 gene test put you into 1 of 3 groups: Normal metabolizer: People in this group are likely to have normal working CYP3A5 proteins. Intermediate metabolizer: People in this group may have reduced activity of CYP3A5 proteins. Poor metabolizer: People in this group may have very little or no active CYP3A5 protein. Learn more about CYP3A5. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.NUDT15
NUDT15
The NUDT15 gene gives instructions to your body to make a protein. It is the job of the NUDT15 protein to break down certain medicines. These medicines include thiopurines and are used in the treatment of cancer, inflammatory bowel disease, and other conditions. Examples of these medicines are Azathioprine, Mercaptopurine, and Thioguanine. The results of your NUDT15 gene test put you into one of 3 groups: Normal metabolizer – People in this group are likely to have normal working NUDT15 proteins. Intermediate metabolizer – People in this group may have reduced activity of NUDT15 proteins. Poor metabolizer – People in this group may have very little or no active NUDT15 proteins. Learn more about NUDT15. Your NUDT15 gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.TPMT
TPMT
The TPMT gene gives instructions to your body to make a protein. It is the job of the TPMT protein to break down certain medicines. These medicines include thiopurines and are used in the treatment of cancer, inflammatory bowel disease, and other conditions. Examples of these medicines are Azathioprine, Mercaptopurine, and Thioguanine. The results of your TPMT gene test put you into one of 3 groups: Normal metabolizer – People in this group are likely to have normal working TPMT proteins. Intermediate metabolizer – People in this group may have reduced activity of TPMT proteins. Poor metabolizer – People in this group may have very little or no active TPMT protein. Learn more about TPMT. Your TPMT gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.Anticancer Treatments
Clúster CYP2C
Clúster CYP2C
The CYP2C (say “SIP-2-see”) cluster gene tells your body how to make a protein. It is the job of the CYP2C cluster protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your CYP2C cluster gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working CYP2C cluster proteins. Decreased function: People in this group may have reduced activity of CYP2C cluster proteins. Poor function: People in this group may have very little or no active CYP2C cluster protein. Learn more about CYP2C Cluster. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctorDPYD
DPYD
The DPYD gene gives instructions to your body to make the DPD protein. It is the job of the DPD protein to break down certain medicines. These medicines include some anticancer treatments, called fluoropyrimidines. Examples of these medicines are: Capecitabine Fluorouracil (5-FU) The results of your DPYD gene test will place you into one of 3 groups: Normal metabolizer – Your genetic test results indicate that you likely have normal working DPYD proteins. Intermediate metabolizer – Your genetic test results indicate that you likely have reduced activity of DPYD proteins. Poor metabolizer – Your genetic test results indicate that you likely have very little or no active DPYD protein. Learn more about DYPD. Your DPYD gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.TPMT
TPMT
The TPMT gene gives instructions to your body to make a protein. It is the job of the TPMT protein to break down certain medicines. These medicines include thiopurines and are used in the treatment of cancer, inflammatory bowel disease, and other conditions. Examples of these medicines are Azathioprine, Mercaptopurine, and Thioguanine. The results of your TPMT gene test put you into one of 3 groups: Normal metabolizer – People in this group are likely to have normal working TPMT proteins. Intermediate metabolizer – People in this group may have reduced activity of TPMT proteins. Poor metabolizer – People in this group may have very little or no active TPMT protein. Learn more about TPMT. Your TPMT gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor. Otro
CYP2C9
CYP2C9
The CYP2C9 gene gives instructions to your body to make a protein. It is the job of the CYP2C9 protein to break down certain medicines. These medicines include: Some nonsteroidal anti-inflammatory drugs (NSAIDs) – used for pain relief Siponimod – used to treat multiple sclerosis Phenytoin and fosphenytoin – used for seizures Warfarin – used to treat and prevent blood clots The results of your CYP2C9 gene test put you into one of 3 groups: Normal metabolizer – People in this group are likely to have normal working CYP2C9 proteins. Intermediate metabolizer – People in this group may have reduced activity of CYP2C9 proteins. Poor metabolizer – People in this group may have very little or no active CYP2C9 protein. Learn more about CYP2C9. Your CYP2C9 gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.CYP2C19
CYP2C19
The CYP2C19 (say “SIP-2-see-19”) gene provides instructions to your body to make a protein. It is the job of the CYP2C19 protein to break down a variety of certain medicines. Only certain medicines are impacted by this gene. The results of your CYP2C19 gene test will place you into one of 5 groups: Normal metabolizer – Your genetic test results indicate that you likely have normal working CYP2C19 proteins. Poor metabolizer – Your genetic test results indicate that you likely have very little or no active CYP2C19 proteins. Intermediate metabolizer – Your genetic test results indicate that you likely have reduced activity of CYP2C19 proteins. Rapid metabolizer – Your genetic test results indicate that you likely have high activity of CYP2C19 proteins. Ultrarapid metabolizer – Your genetic test results indicate that you likely have very high activity of CYP2C19 proteins. Learn more about CYP2C19. Your CYP2C19 gene test may help your doctor pick the right medicine and right dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.CYP2D6
CYP2D6
The CYP2D6 (say “SIP-2-de-6”) gene gives instructions to your body about how to make a protein. It is the job of the CYP2D6 protein to break down certain medicines. These medicines include: Some medicines that help with your mood or attention. Some medicines that are used to treat pain. Some medicines that are used to help with your muscles or fatigue. Eliglustat: Used to treat Gaucher Disease. Metoclopramide: Used to treat slow digestion because of diabetes mellitus or gastroesophageal reflux disease (GERD). Metoprolol: Used to treat some heart conditions or high blood pressure. Ondansetron: Used to treat nausea or vomiting. The results of your CYP2D6 gene test put you into 1 of 4 groups: Ultrarapid metabolizer: People in this group may have increased activity of CYP2D6 proteins. Normal metabolizer: People in this group are likely to have normal working CYP2D6 proteins. Intermediate metabolizer: People in this group may have reduced activity of CYP2D6 proteins. Poor metabolizer: People in this group may have very little or no active CYP2D6 protein. Learn more about CYP2D6. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.CYP3A5
CYP3A5
The CYP3A5 (say “SIP-3-ay-5”) gene tells your body how to make a protein. It is the job of the CYP3A5 protein to break down certain medicines. An example of this medicine is tacrolimus. This medicine is used after transplants and to treat certain skin diseases. The results of your CYP3A5 gene test put you into 1 of 3 groups: Normal metabolizer: People in this group are likely to have normal working CYP3A5 proteins. Intermediate metabolizer: People in this group may have reduced activity of CYP3A5 proteins. Poor metabolizer: People in this group may have very little or no active CYP3A5 protein. Learn more about CYP3A5. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.CYP4F2
CYP4F2
The CYP4F2 (say “SIP-4-ef-2”) gene tells your body how to make a protein. It is the job of the CYP4F2 protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your CYP4F2 gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working CYP4F2 proteins. Intermediate function: People in this group may have reduced activity of CYP4F2 proteins. Poor function: People in this group may have very little or no active CYP4F2 protein. Learn more about CYP4F2. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctor.Clúster CYP2C
Clúster CYP2C
The CYP2C (say “SIP-2-see”) cluster gene tells your body how to make a protein. It is the job of the CYP2C cluster protein to break down certain medicines. An example of this medicine is warfarin. This medicine is used to treat and prevent blood clots. The results of your CYP2C cluster gene test put you into 1 of 3 groups: Normal function: People in this group are likely to have normal working CYP2C cluster proteins. Decreased function: People in this group may have reduced activity of CYP2C cluster proteins. Poor function: People in this group may have very little or no active CYP2C cluster protein. Learn more about CYP2C Cluster. The results of this test can help your doctor choose the right medicine and dose for you. The information you receive through this website is not intended to be medical advice. The information you receive through this website will include genetic test results only. If you need medical assistance, please seek care at an appropriate facility. You should contact your doctor about any genetic test results that you receive from the biobank. Do not stop using or change any of your medicines before speaking with your doctorOUR LAB PLACEHOLDER
More info about lab to come
Biobank stories
Preguntas frecuentes
¿Qué es la medicina personalizada y cómo funciona?
El objetivo de la medicina personalizada es elegir los tratamientos adecuados para cada paciente en función de su composición genética única. Al estudiar la información genética y los registros de salud de un grupo grande y diverso de personas inscritas en el biobanco, los investigadores pueden encontrar nuevas formas de detectar, tratar e incluso prevenir enfermedades.
¿Por qué están haciendo este estudio de investigación?
Estamos inscribiendo a pacientes de todo UCHealth en el estudio del biobanco para aprender cómo las diferencias genéticas entre las personas pueden afectar la salud y la enfermedad. Aprender más sobre esto podría, en el futuro, ayudarnos a hacer descubrimientos que podrían mejorar la atención médica para todos.
¿Qué gano al unirme al biobanco?
Cuando analizamos su muestra genética, también podemos aprender algo que es médicamente relevante para usted. Si firmó un consentimiento de biobanco que nos permite devolver los resultados, es posible que compartamos información médicamente relevante con usted. No podemos garantizar que encontraremos dicha información para dársela.
El objetivo principal de este programa de investigación es ayudar a los investigadores a comprender cómo nuestros genes afectan la salud. Su contribución puede ayudar a promover la investigación necesaria para mejorar la atención médica futura. Estas mejoras pueden ayudarnos a combatir mejor las enfermedades que le afectan a usted, a sus seres queridos, a las generaciones futuras y a la comunidad en general.
¿Me pagarán por participar en el estudio?
No recibirá ningún pago por ser parte de este estudio de investigación. No tendrás que pagar nada para estar en este estudio. No se le cobrará a usted ni a su compañía de seguros por donar una muestra al biobanco.
¿Cuánto cuesta participar? ¿Se me facturará a mí o a mi seguro los resultados genéticos clínicos del biobanco?
La participación en el biobanco y la información inicial de los resultados es gratuita como parte del programa de investigación.
¿Por qué necesitan una muestra genética mía?
Si se inscribe en el biobanco, recolectaremos una muestra de sangre cuando le realicen su próxima extracción de sangre de rutina en un centro de UCHealth. También puede haber oportunidades para proporcionar una muestra de saliva.
Le tomamos una muestra de sangre o saliva para poder examinar su ADN (ácido desoxirribonucleico). El ADN es donde almacenamos la información que heredamos de nuestros padres; Esa información dirige la forma en que crecemos y nos desarrollamos. El ADN contiene su código genético. Vive en cada una de las células de tu cuerpo. Analizamos el ADN para comprender cómo difiere la información genética de las personas. También almacenamos algunas de sus muestras para futuras investigaciones.
¿Cómo se identificará mi muestra?
Al igual que con cualquier muestra proporcionada a un laboratorio, los tubos de recolección de sangre o saliva tienen algunos detalles personales, como su nombre y fecha de nacimiento, para identificar la muestra. Cuando la muestra se utiliza para la investigación, se le asigna un código único y solo el biobanco puede vincular el código a su información personal.
Por lo general, los investigadores fuera del biobanco no tendrán acceso a información que pueda identificarlo directamente, como su nombre, dirección o número de historia clínica. Dicha información puede ser requerida por los investigadores para ciertos tipos de investigación. Esto solo sucedería con el permiso del Comité de Acceso al Biobanco y la Junta de Revisión Institucional Múltiple de Colorado (COMIRB). El COMIRB es un organismo administrativo que protege los derechos y el bienestar de los sujetos humanos de investigación.
¿Cuánto tiempo conservan mi muestra?
Si decide participar en este estudio, no hay límite en la cantidad de tiempo que almacenaremos sus muestras e información de salud. Es posible que sigamos usándolos para la investigación a menos que decida dejar de participar o que cerremos el biobanco. Dado que no hay límite de tiempo para el almacenamiento de muestras, solo tendrá que proporcionar una muestra de sangre o saliva.
¿Puedo ver mi propia muestra genética?
No. Se genera una gran cantidad de información cuando procesamos su muestra. La gran mayoría de ella es información que solo es valiosa para fines de investigación en este momento. Debido al tamaño de los datos y al impacto desconocido, no vamos a devolver los datos a los participantes en este momento.
¿Por qué se me pide que vuelva a dar mi consentimiento para el biobanco?
Sise inscribió anteriormente y se le pide que actualice su consentimiento, es porque el formulario de consentimiento original del biobanco tenía un alcance e información limitados. El formulario de consentimiento actualizado contiene información adicional sobre el estudio de investigación del biobanco, sus derechos como participante, cómo compartimos la información y la posible devolución de los resultados de las pruebas genéticas.
¿Recibiré los resultados de mi muestra genética?
Es posible que aprendamos algo que es importante para su salud cuando procesemos su muestra. Si firmó un consentimiento de biobanco que nos permite devolver los resultados, es posible que podamos devolverle los resultados. Para obtener más información sobre los tipos de resultados que podemos devolver y cómo se devolverán, visite esta página web.
No podemos garantizar que todos reciban los resultados, ya que se trata principalmente de un proyecto de investigación para hacer descubrimientos generales sobre la salud y el riesgo de enfermedades utilizando el análisis de datos de grandes poblaciones. Para muchas personas, no encontraremos ningún resultado de prueba genética clínica relevante para informar. Además, no a todas las muestras de los participantes se les realizarán pruebas genéticas.
¿Recibiré una notificación sobre el tipo de investigación para el que se utilizará mi muestra?
Actualizamos a los participantes sobre los tipos de investigación que se están realizando con los datos del biobanco, pero no podremos decirles a los participantes para qué estudios se utiliza su muestra o sus datos. Los participantes no podrán elegir para qué estudios se utilizarán sus datos.
¿Qué investigación van a hacer con mi muestra?
Usaremos su muestra e información de salud para muchos tipos de investigación, incluidos los estudios que analizan cómo las diferencias en nuestra información genética afectan el riesgo de ciertas enfermedades y cómo procesamos los medicamentos.
¿Cómo se comparte mi información en el biobanco?
Al compartir datos, esperamos ayudar a los investigadores a realizar más investigaciones sobre las condiciones de salud con el objetivo de encontrar mejores tratamientos. Compartiremos los datos sobre los participantes del biobanco con los socios de investigación que tengan las aprobaciones adecuadas. También compartiremos algunos de los datos genéticos que hemos generado en bases de datos como dbGaP, que significa "Base de Datos de Genotipos y Fenotipos" que está patrocinada por los Institutos Nacionales de Salud (NIH). Los datos compartidos con dbGaP se anonimizan para eliminar información personal como nombres, direcciones y fecha de nacimiento. También podemos compartir datos anónimos con socios de la industria, incluidos aquellos que están desarrollando nuevos medicamentos o tratamientos.
¿Qué protecciones existen para mi información y muestra de salud?
Nos tomamos muy en serio la protección de su privacidad. Seguimos las leyes federales de privacidad y las regulaciones de atención médica para proteger su información. Cualquier dato compartido a través de nuestras asociaciones no contiene información personal o de identificación. Toda la información utilizada por el estudio de investigación del biobanco se protegerá mediante computadoras seguras y archivos bloqueados, de modo que solo las personas autorizadas puedan acceder a ella.
¿La información genética está protegida por la ley?
Una ley federal, llamada Ley de No Discriminación por Información Genética (GINA, por sus siglas en inglés), generalmente establece que es ilegal que las compañías de seguros de salud, los planes de salud grupales y la mayoría de los empleadores lo discriminen en función de su información genética. Los estados individuales tienen sus propias protecciones relacionadas con la información genética.
¿Qué pasa si tengo otras preguntas?
Si tiene más preguntas sobre este estudio, llame al biobanco al 303.724.9944 o envíenos un correo electrónico a [email protected].
Si tiene preguntas sobre sus derechos como sujeto de investigación o sobre la realización de este estudio, comuníquese con la Junta de Revisión Institucional Múltiple de Colorado (COMIRB) al 303.724.1055.
Centro de Medicina Personalizada de Colorado
1890 N. Revere Court
Parada de correo F563
Aurora, CO 80045
303.724.9944
[correo electrónico protegido]
Protocolo COMIRB #15-0461
Casey Greene
Retiro del biobanco
Puede retirarse del estudio de investigación del biobanco en cualquier momento. Si desea retirarse, complete nuestro formulario en línea. Una vez retiradas, las muestras no utilizadas serán destruidas. Cualquier información de su muestra que ya se haya utilizado para la investigación no se puede destruir.